Discover how the latest findings from the Electronic Framingham Heart Study shed light on the link between arterial stiffness and home blood pressure variability over time, offering new insights into cardiovascular health.
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Association of Arterial Stiffness With Mid- to Long-Term Home Blood Pressure Variability in the Electronic Framingham Heart Study: Cohort Study.
Wang et al., JMIR Cardio 2024
<!– DOI: 10.2196/54801 //–>
https://doi.org/10.2196/54801
This study explores the relationship between arterial stiffness and mid- to long-term blood pressure variability (BPV) at home, using data from the electronic Framingham Heart Study (eFHS). It specifically examines how arterial stiffness indicators, such as forward pressure wave amplitude (FWA) and reflection coefficient (RC), correlate with the average real variability (ARV) of systolic (SBP) and diastolic (DBP) blood pressure over up to one year. The study found that a one standard deviation increase in FWA was associated with significant increases in ARV of SBP and DBP, as was a one standard deviation increase in RC. However, no significant association was found between carotid-femoral pulse wave velocity (CFPWV) and ARV of SBP or DBP after adjusting for covariates.
Key findings:
– Higher FWA and RC are linked to greater week-to-week BPV at home over a year.
– No significant association between CFPWV and BPV, suggesting specific arterial stiffness measures may differently influence BPV.
This research highlights the importance of considering arterial stiffness traits, like FWA and RC, in understanding and potentially managing BPV in a home setting over time.