Discover the groundbreaking role of navigated transcranial magnetic stimulation and tractography in safeguarding motor function during surgery for motor eloquent gliomas, a pivotal advancement in neurosurgery.
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Significance of navigated transcranial magnetic stimulation and tractography to preserve motor function in patients undergoing surgery for motor eloquent gliomas.
Eibl et al., Heliyon 2024
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https://doi.org/10.1016/j.heliyon.2024.e28115
This study delves into the effectiveness of navigated transcranial magnetic stimulation (nTMS) and nTMS-based tractography for pre-surgical planning in glioma patients, particularly those with tumors near motor areas. By retrospectively analyzing data from 38 surgeries in 36 patients, the research highlights the correlation between postoperative motor function and the proximity of the resection cavity to motor eloquent areas. The findings reveal that a greater distance between the corticospinal tracts (CST) and the resection cavity is associated with stable postoperative motor function. Specifically, the mean distance between the CST and the lesion was 6.9 mm, and the median tumor volume reduction was 97.7%. The study also reports a positive predictive value of 66.7% for permanent deficits after resecting nTMS positive areas, with a negative predictive value of 90.6%. These results underscore the value of preoperative nTMS in enhancing surgical outcomes by aiding in the preservation of motor function, marking a significant contribution to the literature on glioma surgery planning.