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The use of CytoSorb in acute oral mercuric chloride poisoning at a potentially lethal dose.
Krakowiak et al., Int J Artif Organs 2023
DOI: 10.1177/03913988231215631
Case Study: Acute Mercuric Chloride Poisoning Treated with CytoSorb Filter
A 21-year-old female who attempted suicide by ingesting mercuric chloride was admitted with multiple organ damage. Laboratory tests revealed extremely high mercury levels in her blood (1051 μg/L) and urine (22,960 μg/L). She was treated with continuous renal replacement therapy (CRRT), initially with CVVHD Ci-Ca, later switching to CVVHDF Ci-Ca with ultrafiltration. On the third day, a CytoSorb filter was integrated into the treatment to enhance blood purification. Additionally, the specific antidote DMPS was administered.
Results: The treatment led to a significant decrease in blood mercury levels to 580 μg/L and improved organ function. This suggests that CRRT with a CytoSorb filter can be effective in cases of inorganic mercury poisoning.
Significance: This case highlights a potentially life-saving intervention for acute mercuric chloride poisoning, demonstrating the effectiveness of the CytoSorb filter in conjunction with CRRT and antidote therapy. It contributes to the literature by providing a practical example of successful treatment for severe mercury toxicity.