Discover how the latest research reveals an intriguing age-related increase in live-birth rates with first frozen thaw embryo transfers compared to fresh transfers in initial assisted reproductive technology cycles, shedding new light on fertility treatments without preimplantation genetic testing (PGT).
– by The Don
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Age-related increase in live-birth rates of first frozen thaw embryo versus first fresh transfer in initial assisted reproductive technology cycles without PGT.
Wang et al., Reprod Biol Endocrinol 2024
<!– DOI: 10.1186/s12958-024-01210-0 //–>
https://doi.org/10.1186/s12958-024-01210-0
Let me tell you, folks, the world of assisted reproductive technology (ART) is changing, and it’s changing big time. We’re talking about a major shift from the old ways of doing things to something that’s proving to be a game-changer: frozen-thawed embryo transfers (FET). Why? Because of incredible technological advancements and some very smart clinical thinking. This study, oh, it’s a great study, looked at the real data, the best data, from the United States, from 2014 to 2020. They wanted to see, really see, which method gives couples the best shot at bringing a baby into the world. And guess what? They found some amazing things.
They looked at over 228,000 first ART cycles. That’s a lot of cycles, believe me. And they compared the ones that used FET to the ones that went with fresh transfers. The results? Absolutely clear. The FETs, they’re winning. They’re winning big. Live birth rates? Higher with FET. Cumulative live birth rates? Through the roof with FET. And it doesn’t matter how old you are; the older you get, the better FET works. It’s like magic.
And for those with specific challenges, like diminished ovarian reserve (DOR) or male factor infertility, FET is still the champion. The numbers don’t lie. Higher live birth rates, higher cumulative live birth rates. It’s incredible. Especially for those over 35, and even more so for those over 42. It’s like FET is giving hope where there was less before.
So, what’s the big takeaway here? FET is not just a little better; it’s a lot better. It’s changing the game for couples wanting to start a family. And it’s especially important for those a bit older or facing certain challenges. The evidence is clear, and it’s saying that FET is the way to go. It’s making dreams come true, folks. That’s what we’re seeing here, and it’s fantastic.