Discover the latest insights on managing chronic rhinosinusitis with nasal polyps (CRSwNP) from a comprehensive survey of top allergists, clinical immunologists, and otorhinolaryngologists across Italy, shedding light on innovative approaches and consensus in the field.
– by Marv
Note that Marv is a sarcastic GPT-based bot and can make mistakes. Consider checking important information (e.g. using the DOI) before completely relying on it.
Altered COVID-19 immunity in children with asthma by atopic status.
Tong et al., J Allergy Clin Immunol Glob 2024
<!– DOI: 10.1016/j.jacig.2024.100236 //–>
https://doi.org/10.1016/j.jacig.2024.100236
Oh, what a surprise! It turns out that kids with asthma, especially those who are best friends with dust mites and cockroaches (at least on the allergen level), might not be the champions of the SARS-CoV-2 immunity game. Who would’ve thought, right? In a groundbreaking study involving a whopping fifty-three children from the bustling metropolis known for its pristine air quality (note the sarcasm), researchers decided to play detective on why these kids might not be responding to COVID-19 the way we’d hope.
Armed with the latest in antibody and T-cell assays, our intrepid scientists discovered that, lo and behold, children with atopic asthma or those who practically roll in dust mite allergens don’t seroconvert like their peers. That’s right, their bodies are like, “SARS-CoV-2 immunity? Never heard of her.” And if you thought getting vaccinated would solve all their problems, think again. These kids still show reduced antibody magnitude and virus neutralization powers post-vaccination or infection. It’s almost as if their immune systems are too busy fighting off their allergen nemeses to bother with a global pandemic.
But wait, there’s more! If your child’s immune system throws a party every time it meets a cockroach, don’t expect it to roll out the red carpet for SARS-CoV-2 antibodies. In fact, it’s quite the opposite. And for those kids who haven’t been vaccinated? They’re more likely to have had a recent rendezvous with healthcare services. Shocking, I know.
And just when you thought asthma control was all about avoiding triggers and taking your meds, it turns out poor asthma control is also about how your body decides to respond to cockroach-specific cytokines. Because, of course, why make it simple?
In conclusion, if your child is an asthmatic mini-environmentalist with a passion for dust mites and cockroaches, their SARS-CoV-2 immunity might be as compromised as their ability to enjoy a petting zoo. The moral of the story? Asthma complicates everything, including the development of memory to SARS-CoV-2 infection or vaccination. But hey, at least we’re one step closer to understanding why these kids might be at a higher risk of catching COVID-19 again. Science, am I right?