Discover the pivotal insights into the survival rates and historical traits of patients documented in the Swiss Amyloidosis Registry, shedding light on the evolving landscape of amyloidosis treatment and management.
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Historic characteristics and mortality of patients in the Swiss Amyloidosis Registry.
Brouwers et al., Swiss Med Wkly 2024
<!– DOI: 10.57187/s.3485 //–>
https://doi.org/10.57187/s.3485
The interdisciplinary Amyloidosis Network at University Hospital Zurich, established in 2013, has been pivotal in advancing the understanding of systemic amyloidoses through a dedicated registry. This registry, collecting data from 2005 to 2020, included 155 patients diagnosed with systemic amyloidosis across four centers. The study highlighted light-chain amyloidosis (49.7%) and transthyretin amyloidosis (40%) as the most prevalent types, with a significant portion of patients (61.9%) presenting multiorgan involvement. Notably, the median observation time for surviving patients was 3.29 years, with specific survival rates for light-chain and transthyretin amyloidosis patients showing no significant difference (p = 0.81). These findings underscore the high survival rates among these patients, aligning with data from similar international registries. However, the study calls for further research to assess the evolving morbidity and mortality rates in the amyloidosis patient population, emphasizing the dynamic nature of this disease landscape.