Explore the critical insights into the risks and outcomes of malignant cerebral edema following endovascular treatment for acute basilar artery occlusion, as revealed in the comprehensive secondary analysis of the ATTENTION trial.
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Incidence, predictors, and outcomes of malignant cerebral edema in acute basilar artery occlusion after endovascular treatment: a secondary analysis of the ATTENTION trial.
Huang et al., J Neurosurg 2024
<!– DOI: 10.3171/2024.1.JNS232085 //–>
https://doi.org/10.3171/2024.1.JNS232085
This study delves into the occurrence, predictors, and outcomes of malignant cerebral edema (MCE) in patients with acute basilar artery occlusion (BAO) treated with endovascular treatment (EVT), based on data from the ATTENTION trial. It was found that 13.2% of the 189 analyzed patients developed MCE. Key predictors identified include the baseline Glasgow Coma Scale (GCS) score and the number of procedures undergone, with lower GCS scores and a higher number of procedures increasing the risk of MCE. Importantly, the presence of MCE significantly worsened the prognosis, reducing the likelihood of achieving functional independence and a good outcome at 90 days, while increasing mortality rates. This research highlights the importance of early identification and management of MCE in BAO patients undergoing EVT, offering insights that could guide clinical decisions and improve patient outcomes.