Oh, what a joyous day in the world of epilepsy treatment! We’ve stumbled upon a groundbreaking revelation that’s as shocking as finding out water is wet: not all patients with intractable epilepsy can be easily fixed with a quick peek at an MRI. Who would’ve thought, right? Enter the knight in shining armor, Stereo-electroencephalography-guided radio-frequency thermocoagulation (SEEG-guided RF-TC), ready to zap away those pesky seizures without the mess of open surgery. Because, you know, we’re all about that minimally invasive life now.

So, in a thrilling adventure at the Sanbo Brain Hospital (sounds like a place where superheroes are born), 30 brave souls underwent this high-tech procedure between April 2015 and December 2019. Fasten your seatbelts, because the results are about to blow your mind… or maybe just mildly ruffle your hair. A whopping 36.7% of these patients achieved the coveted status of International League Against Epilepsy class 1 by the last follow-up. In layman’s terms, they hit the epilepsy jackpot and became seizure-free. The average time they enjoyed this blissful state? A rollercoaster ride of 21.33 months. But hold your applause, because the median time they actually stayed seizure-free was a less impressive 3 months. Talk about a short-lived victory.

But wait, there’s more! If your epileptogenic zone is chilling in the insular lobe or throwing a solo party in the limbic system, you’re in luck. Your chances of ditching seizures are significantly higher. Who knew that real estate location mattered just as much in your brain as it does in the housing market?

In conclusion, this riveting saga of SEEG-guided RF-TC in the land of MRI-negative epilepsy gives us hope. Hope that one day, we might just be able to guide our surgical interventions as confidently as a GPS navigating through rush hour traffic. Until then, let’s keep zapping away and making those better decisions, one insular lobe at a time.