Discover how the latest breakthrough in orbital fracture treatment can predict and reduce the risk of double vision complications with our in-depth look at the newly developed postoperative diplopia risk calculator.
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Development and validation of a risk calculator for postoperative diplopia following orbital fracture repair in adults.
Hassan et al., Sci Rep 2024
<!– DOI: 10.1038/s41598-024-54121-w //–>
https://doi.org/10.1038/s41598-024-54121-w
The study introduces the first multi-center risk calculator for predicting postoperative diplopia (double vision) after orbital fracture repair (OFR). This is significant because previous research was limited to single institutions and small sample sizes. The study analyzed 254 adult patients from two high-volume trauma centers, excluding those under 18 or with less than two weeks of postoperative follow-up.
The risk model was developed using 70% of the patient data and validated with the remaining 30%. It considered factors such as age, preoperative enophthalmos (sunken eyeball), fracture size and displacement, timing of surgery, globe/soft tissue repair, and medial wall involvement. The model demonstrated excellent accuracy with a C-statistic of 80.4% for discrimination and passed the Hosmer-Lemeshow test for calibration (P=0.2).
Importantly, the model could rule out postoperative diplopia with 100% sensitivity and negative predictive value (NPV) for probabilities below 8.9%. For probabilities below 13.4%, it had a sensitivity of 87.9% and an NPV of 95.8%. This validated risk calculator is a significant contribution to clinical practice, offering a powerful screening tool to predict the risk of postoperative diplopia in adult patients undergoing OFR.
