Frameless vs. Image-Guided: The Future of Brain Biopsies – A Bicentric Study Comparison

Explore the cutting-edge of neurosurgical precision in our latest post comparing the safety and efficacy of frameless stereotactic robot-assisted biopsies to traditional image-guided techniques in brain lesion interventions.
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Safety and efficacy of frameless stereotactic robot-assisted intraparenchymal brain lesion biopsies versus image-guided biopsies: a bicentric comparative study.

Leclerc et al., Acta Neurochir (Wien) 2024
<!– DOI: 10.1007/s00701-024-05912-7 //–>
https://doi.org/10.1007/s00701-024-05912-7

Study Summary:

A comparative study was conducted to evaluate the effectiveness and safety of two different surgical methods for intraparenchymal brain lesion biopsy: frameless robot-assisted stereotactic biopsies and image-guided biopsies. The study included 250 patients from two French university hospitals, with 131 undergoing robot-assisted biopsies and 119 undergoing image-guided biopsies.

Key Findings:

  • The diagnostic yield was similar for both methods (96.2% for robot-assisted and 95.8% for image-guided; p = 1.000).
  • Postoperative complication rates were comparable (13% for robot-assisted and 14% for image-guided; p = 0.880).
  • Robot-assisted biopsies had a longer mean duration (61.9 ± 25.3 minutes) compared to image-guided biopsies (47.4 ± 11.8 minutes; p < 0.001).
  • In patients on anticoagulant/antiplatelet therapy, the incidence of postoperative intracerebral hemorrhage >10 mm was lower in the robot-assisted group (5%) than in the image-guided group (36.8%; p < 0.001).

Importance:

This study contributes to the literature by providing a direct comparison between two modern neurosurgical techniques for brain lesion biopsies. It highlights that both methods are safe and efficient, with the robot-assisted approach having a longer surgery duration but a lower risk of significant postoperative hemorrhage in patients on blood-thinning medications.

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