Discover the latest insights on how muscle strength, rather than muscle mass, could be the key determinant in stroke recovery, transforming our approach to rehabilitation.
– by James
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Muscle weakness is more strongly associated with functional outcomes in patients with stroke than sarcopenia or muscle wasting: an observational study.
Nozoe et al., Aging Clin Exp Res 2024
DOI: 10.1007/s40520-023-02672-9
Study Highlights:
- New Information: This study provides evidence on the independent associations between sarcopenia, muscle weakness, and low muscle mass with functional outcomes in stroke patients.
- Importance: Identifies sarcopenia and related conditions as significant prognostic factors for stroke recovery, highlighting the need for targeted interventions.
- Contribution to Literature: Adds to the understanding of post-stroke complications by using the 2019 Asian Working Group for Sarcopenia criteria to define sarcopenia and related conditions.
Results Summary:
The study included 247 patients with a median age of 73 years. Sarcopenia was present in 28% of patients. After adjusting for confounders, sarcopenia (aOR = 2.60), muscle weakness (aOR = 3.40), and low muscle mass (aOR = 2.61) were significantly associated with poor functional outcomes, as measured by a modified Rankin Scale (mRS) score of 3 or higher at 3 months post-stroke. Muscle weakness had the strongest association with poor outcomes.