Discover the enigmatic world of Pseudoxanthoma Elasticum, a rare condition often mistaken for vasculitis, as we delve into the latest comprehensive literature review that unveils its complexities and challenges in diagnosis.
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Pseudoxanthoma elasticum veiled as vasculitis: shedding light on an uncommon disorder and an in-depth review of the literature.
Murshidi et al., Rheumatol Int 2023
DOI: 10.1007/s00296-023-05509-w
Case Study and Systematic Review on Pseudoxanthoma Elasticum (PXE)
What’s New: A case of a 34-year-old male with suspected large vessel vasculitis, later diagnosed with PXE, is presented alongside a systematic review of PXE case reports from the past decade.
Importance: This work highlights the diagnostic challenges of PXE due to its rare occurrence and diverse clinical manifestations, which can mimic other conditions such as systemic vasculitis.
Contribution to Literature: The case study and review provide insights into the variable presentation of PXE, emphasizing the need for multidisciplinary evaluation, including rheumatology, dermatology, and ophthalmology, to ensure accurate diagnosis and management.
The patient’s severe hemifacial pain and vascular abnormalities initially suggested vasculitis, but cutaneous signs and angioid streaks in the eyes led to the PXE diagnosis. The systematic review, sourced from PubMed, Scopus, and open-access databases, aims to improve understanding and treatment of PXE by examining a range of cases and their management complexities.