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The use of CytoSorb in acute oral mercuric chloride poisoning at a potentially lethal dose.

Krakowiak et al., Int J Artif Organs 2023
DOI: 10.1177/03913988231215631

Ho-ho-ho! Gather ’round, my elves, for a tale not of the North Pole, but of a medical marvel just as magical in its own right. Once upon a recent time, in a land not so far away, a young lass of 21 winters found herself in quite the pickle after a sorrowful attempt to escape her woes with a potion most vile—mercuric chloride.

Upon her arrival at the healing halls, the healers and wise folk were aghast to find her very essence tainted with this toxic brew. Her blood carried a staggering 1051 μg/L of the wicked mercury, and her urine, a shocking 22,960 μg/L! Her organs cried out, besieged by the poison’s cruel embrace, and her kidneys, alas, had ceased their merry filtering dance.

But fear not, for the healers were quick to act! They summoned a magical contraption known as continuous renal replacement therapy (CRRT), a device not unlike my own sleigh in its life-saving capabilities. They began with a spell called CVVHD Ci-Ca, but soon, with a twinkle in their eyes, they switched to the more potent CVVHDF Ci-Ca with ultrafiltration, all to optimize the enchantment.

On the third day, as the stars twinkled with hope, they added a most curious artifact to their arsenal—the CytoSorb filter. This wondrous device, akin to the finest of my toy-making tools, worked tirelessly to cleanse the blood of its mercurial curse.

And what of the antidote, you ask? Ah, the clever healers had not forgotten. They administered a potion known as DMPS, a specific balm to counteract the mercury’s malice. Lo and behold, the young maiden’s complaints began to wane, her blood mercury levels fell to a less fearsome 580 μg/L, and her organs, those joyous instruments of life, began to mend and sing once more.

So let it be known across all lands, from the snowy peaks to the sandy shores, that in the direst of times, when inorganic mercury compounds cast their shadow, the CytoSorb filter, with its extracorporeal blood purification charm, may just be the saving grace. And with that, my dear friends, the story ends not with a “Goodbye,” but with a hopeful “Until we meet again,” for in the world of healing, there’s always another miracle just around the corner. Merry tidings to all, and to all a good health! 🎅🌟

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