Discover the groundbreaking insights into pediatric bone health with newly established BoneXpert-derived reference curves tailored for Indian children and adolescents, a significant stride in assessing and managing bone development in this population.
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BoneXpert-derived bone health index reference curves constructed on healthy Indian children and adolescents.
Oza et al., Pediatr Radiol 2023
DOI: 10.1007/s00247-023-05824-1
New Information:
The study introduces reference Bone Health Index (BHI) curves for Indian children, which are crucial for assessing bone health in this population. This is the first time such curves have been generated for Indian children using BoneXpert.
Importance:
The BHI and its standard deviation score (SDS) are important for comparing bone health against a healthy reference population. The study provides a localized reference for Indian children, which is significant given the previously noted differences between Indian and Caucasian children’s bone health.
Contribution to Literature:
The study contributes to the literature by offering age- and sex-specific BHI reference curves for Indian children aged 2 to 17 years. This allows for more accurate assessment of bone health in Indian paediatric populations.
Results Summary:
– Mean BHI and BHI SDS for the study group were 4.02±0.57 and -1.73±1.09, respectively.
– Median BHI increased by 2.5% to 3% annually up to age 14, then by 4.5% to 5% thereafter.
– Indian children’s mean BHI was lower than that of Caucasian peers, with the largest differences observed in boys at 16 years (21.7%) and girls at 14 years (16%).
– The study sample’s BHI standard deviation was 8.4%.
– Reference percentile curves for BHI were created for both boys and girls.