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Neurodevelopmental outcome of low-risk moderate to late preterm infants at 18 months.
Ryan et al., Front Pediatr 2023
DOI: 10.3389/fped.2023.1256872
Study on Neurodevelopmental Outcomes of Moderate to Late Preterm Infants
New Information: This study provides evidence that moderate to late preterm (MLP) infants, born between 32 and 36+6 weeks gestational age, have significantly lower neurodevelopmental outcomes at 18 months compared to healthy term-born infants.
Importance: With 80% of preterm births falling into the MLP category, understanding their neurodevelopmental outcomes is crucial for early intervention and support strategies.
Contribution to Literature: This research adds to the existing literature by quantifying the neurodevelopmental disparities between MLP and term-born infants using the Griffith’s III assessment.
Results: The study included 75 MLP infants and 92 term control (TC) infants. MLP infants scored significantly lower in the following Griffith’s III subscales:
- Eye-hand coordination (C)
- Personal, Social and Emotional Development (D)
- Gross Motor Development (E)
- General Developmental (GD)
- Foundations of Learning (A)
with p-values < 0.001 for each, except for Foundations of Learning (A) with p = 0.004. The effect sizes (Cohen’s d) ranged from 0.460 to 0.665, indicating moderate effects. No significant difference was found in Language and Communication (B) with p = 0.107.
Conclusion: The study suggests that MLP infants are at risk for neurodevelopmental delays and highlights the need for increased monitoring and intervention for this group.