Tropical Medicine

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Pulmonary hypertension in adults completing tuberculosis treatment.

Allwood et al., Afr J Thorac Crit Care Med 2023
DOI: 10.7196/AJTCCM.2023.v29i3.676

Title: Prevalence of Pulmonary Hypertension in Tuberculosis Patients

What’s New: This study reveals a significant prevalence of pulmonary hypertension (PH) in young patients completing treatment for their first episode of tuberculosis (TB).

Importance: The study contributes to the growing awareness of the association between TB and pulmonary vascular disease.

Results:

  • Out of 100 adult patients, 1 (1%) had PH and 3 (3%) had possible PH.
  • No association was found between PH and sex, age, HIV status, lung function, or 6-minute walking distance.
  • Smoking status was associated with right ventricular systolic pressure (RVSP), but not with the presence of PH.

Contribution to Literature: This study adds to the limited data supporting the inclusion of TB among chronic lung diseases causing PH.

Implications: Given the global prevalence of TB, the absolute number of cases with PH is likely high but underappreciated. Further research in this field is urgently needed.

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